KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC18
All Species:
13.94
Human Site:
S1168
Identified Species:
27.88
UniProt:
Q5T9S5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9S5
NP_996769.2
1454
168962
S1168
Q
R
E
I
E
R
L
S
S
E
L
E
D
M
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537071
1456
169626
S1167
Q
R
E
I
E
R
L
S
S
E
L
E
E
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q640L5
1455
169723
A1169
Q
R
E
I
E
R
L
A
G
E
L
E
D
I
K
Rat
Rattus norvegicus
XP_001060717
1462
170487
T1172
Q
R
E
I
E
R
L
T
G
E
L
E
D
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508531
925
106760
Q665
Q
L
E
K
K
D
Q
Q
F
N
E
Q
E
K
T
Chicken
Gallus gallus
XP_001232490
1295
151316
T1024
K
Q
R
A
A
Q
I
T
Q
L
D
M
T
V
R
Frog
Xenopus laevis
Q9PW73
1335
154049
Q1072
R
R
I
S
E
K
H
Q
D
G
V
D
L
S
K
Zebra Danio
Brachydanio rerio
XP_692712
779
89837
D519
K
T
G
Q
L
E
Q
D
L
L
E
K
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
R1581
Q
V
E
V
S
Q
I
R
S
E
I
E
K
R
I
Sea Urchin
Strong. purpuratus
XP_796315
2152
245292
T1610
Q
R
N
Q
D
N
L
T
S
E
L
Q
D
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
E466
D
L
E
T
M
L
D
E
S
R
A
L
C
S
K
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
N1388
Q
E
Y
S
E
K
I
N
T
L
E
D
E
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
84.4
83.5
N.A.
41.4
49.3
39.8
22.7
N.A.
N.A.
N.A.
20.2
22.9
Protein Similarity:
100
N.A.
N.A.
95.4
N.A.
92.4
91.4
N.A.
51
65.2
59.5
37.2
N.A.
N.A.
N.A.
40
40
P-Site Identity:
100
N.A.
N.A.
80
N.A.
80
80
N.A.
13.3
0
20
0
N.A.
N.A.
N.A.
33.3
46.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
33.3
46.6
46.6
13.3
N.A.
N.A.
N.A.
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
9
9
9
9
9
0
9
17
34
0
0
% D
% Glu:
0
9
59
0
50
9
0
9
0
50
25
42
25
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
17
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
34
0
0
25
0
0
0
9
0
0
17
17
% I
% Lys:
17
0
0
9
9
17
0
0
0
0
0
9
9
9
42
% K
% Leu:
0
17
0
0
9
9
42
0
9
25
42
9
9
9
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% M
% Asn:
0
0
9
0
0
9
0
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
67
9
0
17
0
17
17
17
9
0
0
17
0
0
0
% Q
% Arg:
9
50
9
0
0
34
0
9
0
9
0
0
0
9
17
% R
% Ser:
0
0
0
17
9
0
0
17
42
0
0
0
0
25
9
% S
% Thr:
0
9
0
9
0
0
0
25
9
0
0
0
17
0
9
% T
% Val:
0
9
0
9
0
0
0
0
0
0
9
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _